One labrusca grape that is popular in the American northeast and Midwest is Fredonia. Similar to the Concord grape, Fredonia is characterized by large blue berries and slightly less grapey taste. Fredonia is very popular in Pennsylvania, which possesses a climate and rolling terrain which provides some of the best growing conditions on the east coast.

Like many of the original colonies, winemaking was an instrumental part of the Pennsylvanian society. In 1683 William Penn planted his first vineyard in what is now Fairmount Park in Philadelphia. One hundred years later, the first successful commercial vineyard in the United States was founded in 1787 by Pierre Legaux along the banks of the Schuylkill River nine miles northwest of Philadelphia. Shareholders in his Pennsylvania Vine Company included many prominent Americans of the day, some of whom were Alexander Hamilton, Aaron Burr, Johns Hopkins, and Robert Morris. Over the next hundred years European immigrants brought their wine-making skills to the state, that by 1900 all of Pennsylvania's 67 counties were making wine, with a total production of 195,627 gallons. During Prohibition, all Pennsylvanian wineries were forced to close, however the grape industry survived from juice production – primarily from Welch’s. It wasn’t until 1968 until the Pennsylvanian legislature passed the Limited Winery Act which allowing for commercial wineries. Today, Pennsylvania ranks 4th nationally in the amount of grapes grown (which includes juice grapes) and the state also ranks 8th in the production of wine.

Evergreen Valley Vineyards is a Pennsylvanian winery that is known for producing award-winning classic dry reds and whites made from vinifera and French hybrid grapes. They attempt to cultivate grapes that grow and vinifies well in their location, and Fredonia is a native grape that flourishes in west central Pennsylvania. The winery found a source of high quality Fredonia grapes - and since they only produce 100% varietals – they elected to vinify Fredonia. Their Fredonia is a sweet wine that has a rich purple color and a fruity and distinctive taste. The winery acknowledges that there is a strong vinifera-only culture being promoted today. Even though this portion of the public has a negative outlook upon most of our native grapes, Fredonia being no exception, the winery will continue to produce labrusca wines to accompany their vinifera and hybrid wines.

Maize Valley Winery, in East Central Ohio on the Canal Country Wine Trail, cultivates Fredonia because they wanted to grow a native grape that was vigorous and hardy in their terrior. According to the winery, they prefer Fredonia because the Fredonia grape flavor is less intensive than the other Labrusca grapes such as the Concord. In addition to a good wine, the grape is used to create juice and jelly. The Maize Valley Winery’s Fredonia is semi-sweet with residual sugar at 2.6% that is a very popular summer time wine. This wine won a Silver medal at the Indianapolis Wine Competition. This winter, the winery is introducing a sweet red table wine called Red Neck Red which is a blend of several grapes, in which Fredonia will be the main component.